The American Heart Association
recommends that health care professionals “routinely monitor
body weight (especially the index for central obesity), blood
glucose, lipoproteins and blood pressure; treat individuals'
risk factors ... and carefully choose anti-hypertensive drugs
because different agents have different effects on insulin
sensitivity."
A root cause of obesity is Insulin Resistance, which, in turn,
is a key factor in the development of Metabolic Syndrome, a
major source of damage to your cardiovascular system which is
also known as Syndrome X.
Reversing Insulin Resistance can be a crucial factor in heart
disease prevention because it is a direct link to the weight
gain so often seen in men and women with Metabolic Syndrome.
Insulin is the hormone responsible for allowing glucose, or
blood sugar, to be absorbed by the cells of the body, where it
is converted to energy. If you are Insulin Resistant, your cells
react sluggishly to insulin. When you eat a meal, whether it’s
steak, fish or vegetables, the body breaks it down into a usable
energy form – glucose.
In
a simplified explanation, the food you consume becomes sugar
that will be transported to the tissues, muscles and organs of
the body via the blood stream to be converted into energy.
Following a meal, particularly one that is high in
carbohydrates, you will have elevated levels of glucose in the
blood stream, which signal the pancreas to release even more
insulin until the excess glucose is absorbed by the cells.
When you are Insulin Resistant, excessive amounts of
free-floating glucose remain in the blood stream until they are
sent to the liver and converted to excess body fat. In addition,
hyperinsulinemia (elevated insulin in the blood) encourages your
liver to produce even more triglycerides which are directly
related to a greater risk of heart disease.
"Eating fast food more than twice
a week may double the risk of developing Insulin Resistance."
Insulin Resistance promotes fat storage because
glucose cannot properly enter the cells to be used as energy.
Elevated levels of insulin in the blood stream lead to a series
of biochemical reactions with wide-ranging consequences that can
lead to a variety of other serious health conditions, such as
Cardiovascular Disease, hypertension (high blood pressure), Type
2 Diabetes and some cancers.
The
interactions of Insulin Resistance, obesity and Metabolic
Syndrome are complex and still under medical review. Many
scientists believe that this is a case of "which came first: the
chicken or the egg". Insulin Resistance contributes to obesity
and is an underlying cause of Metabolic Syndrome, while obesity
worsens Insulin Resistance, which then accelerates the
development of Metabolic Syndrome. It is likely that each
disorder exacerbates the other in a vicious cycle.
Because there is no single solution that addresses all the
symptoms of Insulin Resistance or Metabolic Syndrome, you must
rely on a multi-faceted approach to reversing these conditions.
A complete system is required to address the issues presented
by these syndromes – one that includes nutraceuticals (vitamins,
herbs and minerals that are disease specific), a realistic
exercise program combined with nutritional guidance and a
support network that will help you change unhealthy lifestyle
choices.
Overweight Men Face Double Threat From
Prostate Cancer
Overweight and obese men run a double risk of developing prostate cancer, according to another new study.
It suggests that a man's weight may "mask" the accuracy of a
common test to detect prostate cancer, with researchers warning
that doctors could be missing this dangerous cancer in obese
men.
Between the years 2001–04, a team at San Antonio's University of
Texas Health Science Center studied 2,799 men who were free of
prostate cancer. In results released online in the journal
Cancer, researchers reported finding that the more obese men
were, the lower their levels of prostate-specific antigen or PSA.
A man’s PSA of 4.0 or lower usually means no cancer and the
study results were surprising because prostate cancer has been
shown in previous studies to be more aggressive in obese men
than males of average weight. The Texas researchers wanted to
discover whether the detection of cancer was somehow being
delayed in obese men.
The study found that obese men have PSA levels that are about
30% lower than males of normal weight. "That tells us it’s
likely or it’s possible that prostate cancer detection may be
delayed in overweight or obese men," said Jacques Baillergeon,
Associate Professor of epidemiology at the University of Texas
Health Science Center.
It did not explain why obese men have lower PSA levels. But
doctors believe obese men produce more estrogen, which drives
down testosterone levels and could affect the antigen used in
the PSA test.
The research may spur many doctors to take a closer look at the
test results of obese male patients. "For sure, I will be more
vigilant in my patients, who are obese, in evaluating their PSA,"
said Dr. Nelson Stone of Mount Sinai School of Medicine in New
York City, who was not involved in the study.
Dr Stone added that colleagues might be losing some of the PSA
test’s sensitivity, reducing its ability to detect prostate
cancer in obese patients. "We may have to set our sights lower,"
he said.
The antigen used in the PSA test is made by normal prostate
cells and is measured in blood. The higher the antigen level,
the more likely the chance of prostate cancer, according to the
American Cancer Society. But having a high PSA level is not a
definitive diagnosis of cancer, which is why the Atlanta-based
Society recommends that men with high PSA levels should have a
biopsy.
The Texas study builds on previous research released in May last
year in the New England Journal of Medicine which found that 15%
of men with a "normal" PSA actually had prostate cancer and that
two-thirds of those men had aggressive cases.
Many people are unaware that they are suffering from Metabolic
Syndrome, even though the American Heart Association estimates
that 20–25% of the adult population of the U.S. have this
disorder – between 58 and 73 million men and women.
Metabolic Syndrome is characterized by having at least three of
the following symptoms:
Insulin Resistance (when the body can’t absorb blood sugar or insulin properly)
Abdominal fat – in men this means a 40 inch waist or larger, in women 35 inches or larger
High blood sugar levels – at least 110 milligrams per deciliter (mg/dL) after fasting
High triglycerides – at least 150 mg/dL in the blood stream
Low HDL (the "good" cholesterol) – less than 40 mg/dL
Prothrombotic state (a precursor of Cardiovascular Disease)
"I have been on the Insulite
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Santa Ana, CA
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Boise, Idaho
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"Researchers agree that insulin
resistance is central to the metabolic syndrome. When target
cells are unresponsive to insulin, the pancreas responds by
pouring even more insulin into the bloodstream, leading to high
levels of the hormone in the blood, a condition called
compensatory hyperinsulinemia. The high level of insulin in the
blood forces glucose into cells but also starts the events
leading to arterial damage and eventually a heart attack. Under
these conditions, a person may not manifest either diabetes or
heart disease but could well be on the way to either or both."
"I wanted to let you know how much I
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MS
Stuarts Draft, VA
"Simply losing 5-7% of your body fat (typically 10-15 pounds) and increasing your physical activity by taking a brisk walk 4-5 times a week can reduce your risk of developing Type
II Diabetes by almost 60%."
"I started your product and found
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"A non-pharmacologic treatment for these
patients is needed, since drugs prescribed to lower blood
pressure have been shown to actually worsen carbohydrate and
lipid metabolism in Syndrome X patients, negating the beneficial
effects of those drugs."
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the Insulite System has made in how I feel. My appetite has
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PR
Bakersfield, CA
"...approximately 90% of
overweight Hispanic children with a family history for type 2 diabetes have at least one
feature of the metabolic syndrome and 30% possess the metabolic syndrome.
Our results support the view that improving insulin resistance may be crucial in the prevention
of both type 2 diabetes and premature cardiovascular disease in this at-risk subpopulation
of Hispanic youth."